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KMID : 0363219940320050853
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Korean Journal of Dermatology
1994 Volume.32 No. 5 p.853 ~ p.859
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Comparative Histopathologic and Immunohistochemical Studies of Epidermal Cysts of Palm & Sole, Other Epidermal Cysts and pilar Cysts
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Abstract
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Background:
@EN Epidermal cysts are the commonest type of epithelial cysts of the skin. These cysts are lined by stratified squamous epithelium that is identical to that seen in the normal interfollicular epidermis. Less than 10% of these cysts occur on the
extremities, and they are rare on the palms and soles, where they probably reults from traumatic implantation of epidermis. Histopatholoigcally the compact pattern of keratinous materials within the epidermal cyst of palm & sole are similar to
that
within the pilar cyst rather than any other epidermal cyst.
@ES Objective:
@EN The purpose of our study is to compare the biochemical characteristics of keratin in the epidermal cyst of palm & sole, other epidermal cyst and pilar cyst.
@ES Methods:
@EN We evaluated the clinical and histopathologic of 17 cases which were diagnosed with epidrmal cysts of palm & sole at the department of dermatology in Wonju Christian Hospital, Shinchon Severance Hospital and Youngdong Serverance Hospital,
from
January 1981 to June 1993. The immunohistochemical staining (PAP method) using monoclonal antibody against cytokeratin was performed on epidermal cyst of palm & sole, other epidermal cyst and pilar cyst. The extent of the staining was graded by
the
stained cell layer in the cystic wall from negative(-) to diffuse(++).
@ES Results:
@EN The ratio of males to females was 3.2:1. Age distribution at first visit was variable, ranging from 5 to 48 years old. The mean duration of lesions was 1.6 years. The ratio of palms to soles was 1 : 2.4. Histopathologically the cystic wall
was
usually composed of normal squamous epithelium. The most common pattern of keratinous cystic content was a compact one. In epidermal cyst of palm & sole, other epidermal cyst and pilar cyst, the cystic wells were diffusely stained through all
epidermal
layer with LP34. The cystic wall of other epidermal cyst was more strongly stained with 34βE12 than epidermal cyst of palm & sole, pilar cyst.
@ES Conclusion:
@EN The keratin expression by immunohistochemical staining on epidermal cyst of palm & sole was similar to pilar cyst rather than to other epidermal cyst. (Kor J Dermatol 1994 ; 32(5) : 853~859)
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